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Revista Portuguesa de Pneumologia

Print version ISSN 0873-2159

Rev Port Pneumol vol.13 no.1 Lisboa Jan. 2007


Tomografia emissora de positrões: Indicações no cancro do pulmão – Experiência prospectiva de um serviço

Positron emission tomography: Indications in lung cancer – Prospective experience of a department

Diva Ferreira1

A Oliveira1

A Barroso2

A Conde2

B Parente3



A tomografia emissora de positrões (PET) é uma tecnologia recente no âmbito da medicina nuclear. Utiliza radionuclídeos biológicos como o 18F-fluoro-2-deoxy-D-glicose (FDG) permitindo detectar locais onde o metabolismo está aumentado, como no caso de células neoplásicas. Tem vindo a tornar-se um inovador e importante meio imagiológico no cancro do pulmão. Recomendações actuais incluem o diagnóstico de cancro do pulmão, bem como o estadiamento loco-regional e à distancia do CPNPC.

Palavras-chave: Tomografia emissora de positrões, cancro do pulmão, diagnóstico, estadiamento.



Positron emission tomography (PET) is a new technique in nuclear medicine. It uses biological radiotracers such as 18F-fluoro-2-deoxyglucose (FDG) which permit the detection of suspected lesions with metabolic alterations that take up the glucose isotope too avidly, as is the case with neoplastic cells. PET has become an innovatory and important imaging tool for evaluating patients with lung cancer. The present recommended uses of PET include lung cancer diagnosis and the intrathoracic and extrathoracic staging in N-SCLC.

Key-words: Positron emission tomography, lung cancer, diagnosis, staging.


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Bibliografia / Bibliography

1. Gibson G, Geddes D. Scintigraphic imaging. Respiratory Medicine 2003, 3ª edição, Vol 1, 7:352-69.        [ Links ]

2. Gibson G, Geddes D. Clinical features and assessment of lung cancer. Respiratory Medicine 2003, 3.ª edição, Vol 2, 70:1828-49.

3. Hollings N, Shaw P. Diagnostic imaging of lung cancer. Eur Resp J 2002; 19:722-42.

4. Valk PE, Pounds TR. Staging non-small cell lung cancer by whole body fluorodeoxyglucose positron emission tomography. Annu Rev Med 2002; 53:89-112.

5. Vansteenkiste JF, Stroobants SG. Mediastinal lymph node stagin  with FDG-PET. Chest 2001; 120:1791-7.

6. Bénard F, Sterman D. Metabolic imaging of malignant pleural mesothelioma with fluorodeoxyglucose positron emission tomography. Chest 1998; 114:713-22.

7. Patz EF. Imaging lung cancer. Semin Oncol 1999; Suppl (15) 26:21-6.

8. Pieterman RM, van Putten. J. Preoperativ staging of NSCLC with PET. N Engl J Med 2000:414-26.

9. The Noninvasive Staging of Non-small Cell Lung Cancer. Chest 2003; 123:147S-56S.

10. Lowe VJ, Patz EF. Pulmonary abnormalities and PET data analysis: a retrospective study. Chest 2001; 120:521-7.

11. Weder W, Schmid RA. Detection of extrathoracic metastases by fluorodeoxyglucose positron emission tomography in lung cancer. Chest 2003; 123:89S-96S.

12. Urschel JD, Anderson TM. The Solitary Pulmonary Nodule. Chest 2003; 123:147S-56S.

13. Steinert HC, Hauser M. Staging of Lung Cancer with integrated PET-CT. N Engl J Med 2004; 350:121-32.

14. Marom EM, McAdams HP. Imaging techniques for Diagnosis and Staging of Lung cancer. Clinics in Chest Medicine 2002; Vol 3, 13:147-58.


1 Interna complementar de Pneumologia do Centro Hospitalar de Vila Nova de Gaia / Complementary Internship, Pulmonology, Centro Hospitalar de Vila Nova de Gaia

2 Assistente Hospitalar de Pneumologia do Centro Hospitalar de Vila Nova de Gaia / Hospital Assistant, Pulmonology, Centro Hospitalar de Vila Nova de Gaia

3Responsável da Unidade de Pneumologia Oncológica do Centro Hospitalar de Vila Nova de Gaia / Head, Lung Cancer Unit, Centro Hospitalar de Vila Nova de Gaia


Recebido para publicação/received for publication: 06.06.12

Aceite para publicação/accepted for publication: 06.07.31