Abstract

CARVALHO, Joana R. et al. Signet Ring Cell Carcinoma, Ileal Crohn Disease or Both: A Case of Diagnostic Challenge. GE Port J Gastroenterol [online]. 2018, vol.25, n.1, pp.47-51. ISSN 2341-4545.  https://doi.org/10.1159/000479590.

Signet ring cell carcinoma is a rare form of adenocarcinoma that predominantly affects the stomach. Signet ring cell carcinoma originated from the ileum is extremely rare and the prognosis is poor. We present a case of small bowel obstruction with features suggesting Crohn disease of the ileum. The symptoms were chronic diarrhea and abdominal pain with a family history of inflammatory bowel disease. The patient underwent surgery and histopathology revealed both aspects of signet ring cell carcinoma and Crohn disease of the ileum. An association between long-standing inflammation and the development of this subtype of tumor has been proposed but there are no established surveillance guidelines for small bowel neoplasm in inflammatory bowel disease.

Keywords : Signet ring cell carcinoma; Crohn disease; Ileum.

        · abstract in Portuguese     · text in English     · English ( pdf )