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GE-Portuguese Journal of Gastroenterology

Print version ISSN 2341-4545

Abstract

MOTA, Catarina et al. Multisystemic Sarcoidosis with Early Gastrointestinal Symptoms. GE Port J Gastroenterol [online]. 2017, vol.24, n.3, pp.137-141. ISSN 2341-4545.  http://dx.doi.org/10.1159/000450899.

Sarcoidosis involving the digestive tract is very rare and requires a strict differential diagnosis with other systemic granulomatous diseases. We present a case of multisystemic granulomatosis involving the stomach and colon, causing initial digestive symptoms. Pulmonary nodules, pleural effusion, ascites, hepatomegaly, splenomegaly, and mesenteric as well as retroperitoneal and axillary lymphadenopathy were subsequently identified. The reticulo-endothelial expression, the hypercalcemia and, above all, a rapid and complete  resolution after corticosteroids supported the hypothesis of sarcoidosis involving the digestive tract. A brief review of digestive tract involvement in sarcoidosis and of the distinctive features of sarcoidosis with gastrointestinal involvement and Crohn’s disease with a rare form of pleuropulmonary involvement is presented.

Keywords : Crohn’s disease; Gastrointestinal diseases; Sarcoidosis/complications.

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