Abstract

SILVA, Monyque et al. Obesity associated with vitamin d deficiency in patients with heart failure. Acta Port Nutr [online]. 2020, n.22, pp.10-14. ISSN 2183-5985.  https://doi.org/10.21011/apn.2020.2203.

Introduction: Heart failure is associated with a large number of risk factors, including overweight, obesity and stress. Modifiable risk factors can be managed to significantly decrease the risk of developing the disease, such as investigating metabolic biomarkers, such as vitamin D. However, there is little evidence in the guidelines on the association of vitamin D as a risk factor in the population with heart failure. Objectives: To evaluate vitamin D levels as a risk factor associated with obesity in patients with heart failure. Methodology: Observational, cross-sectional and prospective study carried out in a multiprofessional clinic specialized in heart failure. The diagnosis of nutritional status was performed using the validated mini-nutritional assessment questionnaire (MNA), anthropometry. Blood collection was carried out following biosafety recommendations. Data distribution was assessed using the Kolmogorov-Smirnov and Shapiro-Wilk tests. A p value <0.05 was considered significant. Statistical analysis was performed using the Software Statistical Package for the Social Sciences, version 20.0. Results: 76 patients were evaluated, 51.3% with functional class II (New York Heart Association). Regarding nutritional status, 58% had a risk score (MAN) and 75.1% were overweight and obese; serum vitamin D levels are significantly lower in the obese group (80%; p=0.003); waist circumference measurements are significantly higher in the obese group (p=0.020); nutritional risk scores (MAN) are significantly higher in the group with obesity (p<0,001). Vitamin D insufficiency increased the chance of developing obesity (OR: 4.5; 95% CI: [1,1-19,2]). Conclusions: The investigation made it possible to identify a phenotype with a higher risk and was useful for detecting vitamin D insufficiency as a risk factor associated with obesity in outpatients with heart failure.

Keywords : Nutritional assessment; Nutritional status; Cardiac insufficiency; Obesity; Overweight; D vitamin.

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