Abstract

SILVA, Vanessa Filipa Guedes et al. Immunisation against the papillomavirus in males of pediatric age: what’s the evidence?. Rev Port Med Geral Fam [online]. 2019, vol.35, n.5, pp.382-391. ISSN 2182-5173.  https://doi.org/10.32385/rpmgf.v35i5.12272.

Objective: To evaluate the efficacy of the vaccination against the human papillomavirus (HPV) in males in pediatric age, in the prevention of malignant or pre-malignant HPV-associated lesions. Data sources: PubMed, Cochrane Library, DARE, National Guideline Clearinghouse, Canadian Medical Association Practice Guidelines InfoBase, Guidelines Finder (National Electronic Library for Health NHS England). Methods: Search of articles published between 01/01/2006 and 01/09/2019, using the MeSH terms ‘papillomavirus vaccines’, ‘male’, ‘children’, and ‘adolescent’. Male individuals of pediatric age, immunised against HPV for prevention of malignant and pre-malignant HPV-associated lesions were included. The level of evidence was graded according to The American Academy of Family Physicians’ Strength of Recommendation Taxonomy Scale (SORT). Results: In the three clinical guidelines included, male vaccination for HPV in males of pediatric age is recommended with strength of recommendation A. Of the 11 articles included, the majority considers that immunization against HPV in males of pediatric age reduces the incidence of HPV infection, and of malignant and pre-malignant lesions. Conclusion: Immunisation against HPV is effective in preventing HPV lesions and is therefore recommended in males in pediatric age (strength of recommendation A). The vaccination of individuals of both genders is more effective than female vaccination only.

Keywords : Adolescent; Children; Male; Papillomavirus vaccine.

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