SciELO - Scientific Electronic Library Online

 
vol.14 issue3Prevalence and clinical characterisation of patients with severe partial respiratory failure admitted to an intensive care unitEchocardiograph alterations in asthma patients author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Portuguesa de Pneumologia

Print version ISSN 0873-2159

Abstract

CAPUCHINHO-JUNIOR, Geraldo Andrade; DIAS, Ricardo Marques  and  CARVALHO, Sônia Regina da Silva de. One hour effects of salbutamol and formoterol on blood pressure, heart rate and oxygen saturation in asthmatics. Rev Port Pneumol [online]. 2008, vol.14, n.3, pp.353-361. ISSN 0873-2159.

Aim: To analyse systolic (SBP) and diastolic blood pressure (DBP), partial oxygen saturation (SpO2) and heart rate (HR) disorders for an hour after short and long acting ß2-agonists. Material and methods: Twenty-four severe persistent asthma Pulmonology outpatients at Hospital Universitário Gaffrée e Guinle were selected. SBP, DBP, SpO2 and HR values were determined before and after 400 µg of salbutamol and 12 µg of formoterol, on different days, with a minimum interval of 24 hours. Results: All patients showed ventilatory obstruction, as seen by a reduced FEV1/FVC ratio. There was no statistical SBP/DBP/HR difference after bronchodilator agents, but SpO2 increased with salbutamol. Conclusion: A standard dose of salbutamol and formoterol does not cause haemodynamic disorder.

Keywords : Asthma; bronchodilator agents/adverse effects; heart rate; blood pressure; oxygen saturation.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf )