Abstract

VIDEIRA, Paula Alexandra; BORREGO, Luís Miguel  and  TRINDADE, Hélder. Asthma genetic factors. Rev Port Pneumol [online]. 2006, vol.12, n.6, pp.683-708. ISSN 0873-2159.

Asthma is a chronic inflammatory airways disease, with a rising prevalence, particularly in childhood, and is considered an important Public Health problem. It’s familial transmission is recognised, while the description and identification of the genes implicated in this disease are a challenge. In this revision paper the authors give a comprehensive explanation of the associated genes as well as the laboratorial methods that allow their identification.

Keywords : Asthma; genetic susceptibility; genome wide screen; association studies; pharmacogenetics.

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