Abstract

JAFRY, Nazrul Hassan et al. Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report. Port J Nephrol Hypert [online]. 2019, vol.33, n.2, pp.118-121. ISSN 0872-0169.  https://doi.org/10.32932/pjnh.2019.07.024.

We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.

Keywords : Myeloma casts; acute tubular injury; HIV; anti-retroviral therapy.

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