Resumo

ALVES, Rita V et al. Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis?. Port J Nephrol Hypert [online]. 2019, vol.33, n.2, pp.87-90. ISSN 0872-0169.  https://doi.org/10.32932/pjnh.2019.07.019.

Introduction and Aim:Hepatitis C virus screening using anti-HCV antibody is recommended for end-stage renal disease and chronic hemodialysis patients. Since the anti-HCV antibody test is not able to differentiate a concurrent infection from a resolved past one, a more reliable and cost-effective screening test is needed. Materials and Methods: Prospective study of end-stage renal disease and chronic hemodialysis patients from a hospital unit who were screened by anti-HCV antibody and total ARCHITECT® HCV antigen assay. Results: Cohen's κ test was run to determine if there was agreement between HCV Ribonucleic Acid and HCV core antigen assays on 7 individuals with positive anti-HCV antibody. The two tests had a perfect measurement agreement. Conclusions: HCV core antigen testing could be used as a sensitive method for HCV infection screening in this group of patients based on its accuracy, simplicity and low expense

Palavras-chave : Anti-HCV antibody; Diagnosis; HCV RNA; Infection.

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