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Portuguese Journal of Nephrology & Hypertension

Print version ISSN 0872-0169

Abstract

MENDONCA, Luís et al. Recurrence of oxalate nephropathy after renal transplantation in a patient with polyarteritis nodosa: a case report. Port J Nephrol Hypert [online]. 2019, vol.33, n.1, pp.54-57. ISSN 0872-0169.  http://dx.doi.org/10.32932/pjnh.2019.04.010.

Hyperoxaluria is an important complication of short bowel syndrome (SBS) and a non-negligible cause of chronic kidney disease (CKD). We describe the case of a 56-year-old woman with polyarteritis nodosa (PAN) and SBS who was admitted for acute kidney injury (AKI) 2 months after a successful deceased donor kidney transplantation. The diagnostic investigation was consistent with the diagnosis of oxalate nephropathy (OxN) and a set of lifestyle and therapeutic measures was implemented aiming at the reduction of intestinal oxalates absorption. Despite the short-term benefit of this strategy, a progressive and inexorable deterioration of renal function was observed. In this report, we discuss the limited therapeutic options, the ominous prognosis and the risk of recurrence of this rare entity after renal transplantation. Additionally, we reflect on the value of patient compliance in the successful management of the disease and review potential new strategies that may improve the clinical course of this entity in the future

Keywords : Hyperoxaluria; short bowel syndrome; kidney transplantation; polyarteritis nodosa.

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