Abstract

FONSECA, Margarida et al. Renal sarcoidosis presenting as renal failure: report of three cases with interstitial nephritis and normocalcemia. Port J Nephrol Hypert [online]. 2013, vol.27, n.4, pp.301-308. ISSN 0872-0169.

Sarcoidosis is a chronic inflammatory disorder of unknown cause. The histopathological feature is the presence of the non-caseating granuloma in any organ involved. The mechanisms most frequently implicated in renal dysfunction are due to disturbances in calcium metabolism; more rarely, granulomatous interstitial nephritis and glomerular disease may occur. The authors report three cases of sarcoidosis presented as interstitial nephritis with renal failure. Prednisolone treatment was performed at a dose of 1 mg/kg/day with partial and sustained recovery of renal function.

Keywords : Acute kidney injury; granulomatous interstitial nephritis; prednisolone; sarcoidosis.

        · abstract in Portuguese     · text in English     · English ( pdf )