SciELO - Scientific Electronic Library Online

 
vol.22 número4Peak nasal inspiratory flow e testes de odores na rinite índice de autoresíndice de assuntosPesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Revista Portuguesa de Imunoalergologia

versão impressa ISSN 0871-9721

Resumo

ITIKAWA, Ana; MALLOZI, Marcia C; WANDALSEN, Gustavo F  e  SOLE, Dirceu. Skin reactivity to inhalant allergens in allergic children and adolescents from a specialized outpatient clinic: Value of the skin index. Rev Port Imunoalergologia [online]. 2014, vol.22, n.4, pp.257-266. ISSN 0871-9721.

Rationale: Skin prick test (SPT) is an important tool in the evaluation of allergic sensitization and can be influenced by several factors. Skin index (ratio of allergen‑induced wheal diameter and corresponding histamine diameter; SI) have been used to improve the diagnostic power of SPT, especially in young children. Objective: To evaluate the SI in identifying allergic sensitization in patients followed at a specialized pediatric clinic. Material and methods: SPT of 1662 patients performed, between 2009 and 2014, to inhalant allergens, negative control (saline) and positive control (histamine, 1mg/mL) (IPI‑ASAC ® Brazil) were analyzed. Mean wheal diameters of allergens, histamine and negative control were recorded, according to different ages. All patients had a histamine positive SPT (wheal diameter equal or higher than 3 mm). Results: Skin reactivity to histamine increased significantly with increasing age. D. pteronyssinus and B. tropicalis were the predominant inhalant allergens identified. SI cut‑off points for the diagnosis of allergic sensitization were 0.6 for dust mites. However, when applying SI alone as the single diagnostic criteria for sensitization, we observe a reduction in the prevalence of sensitized patients. Conclusions: SI should be used in addition to SPT for the diagnosis of allergic sensitization in those patients who, despite of having low skin reactivity, had SI above 0.6 for D. pteronyssinus or B. tropicalis.

Palavras-chave : Adolescents; allergic sensitization; children; histamine; inhalant allergens; skin index; skin prick tests.

        · resumo em Português     · texto em Português     · Português ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons