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Revista Portuguesa de Imunoalergologia

Print version ISSN 0871-9721

Abstract

DIAS, José Geraldo et al. Recurrent anaphylaxis in a child. Rev Port Imunoalergologia [online]. 2012, vol.20, n.4, pp.291-295. ISSN 0871-9721.

Background : When anaphylaxis occurs, is important to identify its etiology because its treatment involves triggers’ avoidance. Case report: Eight-year-old boy with mild asthma and nonatopic persistent rhinitis, which experienced his first episode of anaphylaxis at 6 years old. Later, he had new episodes, all of them without any triggering factor identified. We noticed that he was treated with paracetamol or ibuprofen before the episodes and an oral challenge test with paracetamol was performed, which was positive, triggering a new episode of anaphylaxis. Ibuprofen had been administered by his mother, without adverse reaction. Skin tests, serum specific IgE and basophil activation test with paracetamol were performed and were all negative. Discussion: This case illustrates anamnesis’ difficulties in determining the etiology of an episode of anaphylaxis. This patient should always carry self-injectable epinephrine device, because there are a lot of over-the-counter drugs with paracetamol in its composition, which could be responsible for accidental ingestion that may contribute to a new episode

Keywords : Anaphylaxis; child; paracetamol.

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