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Arquivos de Medicina

versão On-line ISSN 2183-2447

Resumo

DIAS, Álvaro Machado. Dominance and lull: mapping and integrating psychobiological and the ecological determinants of primary sexual ration in humans. Arq Med [online]. 2014, vol.28, n.6, pp.172-182. ISSN 2183-2447.

Context: until recently, it was believed that the primary sexual reason (masc./fem. offspring) was a stochastic phenomenon, despite anecdotic findings, like alterations in the beginning of wars and in periods of natural catastrophe, pointed in the opposite direction. Recently, these findings were generalized and several hypotheses were raised. Objective: This study aims to 1. Review and categorize the different proximal level causal mechanisms involved in the phenomenon and incorporate the main non-stochastic factors in an algorithm; 2. Present the most prominent biochemical cascade involved; Mine the literature on sexual reason and the most important hormone involved in non-stochastic effects. Methods: All studies of interest on this matter were compiled and carefully discussed in the reviewing sections of the paper, leading to the emergence of the algorithm and the epidemiological equation. The biochemical cascade was based on suggestions of the literature and implemented using KEGG (http://www.genome.jp/kegg/tool/search_pathway.html). Data mining was based on Omniviz and PubMed records. Results: sexual reason is profoundly affected by psychological and seems to primarily involve the amount of maternal testosterone. The literature on the matter is scarce and mainly reduced to studies on animal.

Palavras-chave : sexual reason; psycho-endocrinology; bioinformatics; data mining; evolution.

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