Abstract

RODRIGUES, Ana; BALDAIA, Helena  and  CARNEIRO, Fátima. Primary liver tumors in pediatric population: from pathology to clinic. Arq Med [online]. 2013, vol.27, n.3, pp.104-114. ISSN 2183-2447.

Primary liver tumors in children and adolescents include a wide and complex spectrum of epithelial, mesenchymal and vascular neoplasms, ranging from benign, incidentally discovered lesions to malignant entities. A high level of suspicion is usually required for an early diagnosis of these tumors, due to their rarity and unspecific clinical presentation. The current knowledge on the clinical, analytical and imaging features as well as on the (molecular) pathology profile contributes for an earlier diagnosis, with prognostic and therapeutic implications. This paper reviews the epidemiology, etiopathogenesis, histopathology and molecular features of the most common primary liver tumors in pediatric population.

Keywords : Liver; pathology; pediatric liver tumor; epithelial neoplasms; mesenchymal neoplasms; vascular neoplasms.

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