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Arquivos de Medicina
On-line version ISSN 2183-2447
Abstract
CAEIRO, Cláudia et al. Estesioneuroblastoma: Caso Clínico e Revisão da Literatura . Arq Med [online]. 2008, vol.22, n.1, pp.21-23. ISSN 2183-2447.
Esthesioneuroblastoma is a rare malignancy arising from the olfactory epithelium with no established standard of care. A combined approach of craniofacial resection (CFR) followed by radiotherapy (RT) appears to provide the best outcome. Chemotherapy (CT) tends to be reserved for locally advanced tumors. Histological grade, tumor stage and cervical node involvement have been correlated with prognosis. We report on a 17 year-old male with a Kadish stage C tumor submitted to CFR followed by RT and CT. Three months after completion of therapy, he had an extensive left frontal relapse and was initiated on supportive care dying 12 months after diagnosis. Following this case, a review of the literature is undertaken.
Keywords : esthesioneuroblastoma; craniofacial resection; radiotherapy; chemotherapy; immunohistochemistry.