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Arquivos de Medicina

On-line version ISSN 2183-2447


VEIGA, Mariana Novais et al. Mixed connestivite tissue disease . Arq Med [online]. 2005, vol.19, n.4, pp.149-151. ISSN 2183-2447.

The authors report a case of a 24 -year-old female in is first pregnancy, hepatitis B carrier, with mixed connective tissue disease, wich belongs to a very problematic family (husband with chronic hepatitis C and brother with co-infection HIV-HCV and toxicodependent). The diagnosis was confirmed 3 years ago and the disease was in remission for more than 6 months ago. In this case, in constrast to what we found in the literature, there was a very serious complication in the central nervous system putting at risk the mother’s life. The multidisciplinary team had many doubts in decide the best treatment, the use or not of teratogenic drugs and the moment to interrupt the gestation. We wonder if agressive treatment to prevent mixed connective tissue disease exacerbation may be appropriate during pregnancy.

Keywords : Case report; mixed connective tissue disease; pregnancy; immunosupressive drugs.

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