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Revista de Ciências Agrárias

Print version ISSN 0871-018X

Abstract

RIBEIRO, Maria. Agrimonia eupatoria L.: Pharmacological activity and medicinal interactions. Rev. de Ciências Agrárias [online]. 2017, vol.40, n.spe, pp.321-330. ISSN 0871-018X.  https://doi.org/10.19084/RCA16183.

In recent years there has been, worldwide, a considerable increase in the consumption of medicinal plants. This research aimed to describe and characterize the Agrimonia eupatoria L. about pharmacological properties and medicinal interactions. Taking into account the constituents, the plant exhibits pharmacologic and therapeutic action, anti-diabetic, antitumor, antibacterial, antiviral, dermatological, gastrointestinal, diuretic, metabolic, antidiarrheal, bile duct, hepatoprotective, analgesic, antihypertensive, immunomodulatory, urolithic, cardioprotective, antirheumatic, antioxidant, anti-inflammatory and anticoagulant. When taken in excessive doses, the constituents of the plant may interact with therapies that use anticoagulation and antihypertensive therapy and, in general, with the action of other medicaments metabolized in the liver. Pharmacokinetic interactions of the potentiation synergism type were found with anticoagulants and antihypertensive medicines. Despite the intensification of research on medicinal plants, many of their interactions with other medicaments are still unknown. Nevertheless, most users do not report their use to the health professional. As advocated by several researchers in clinical practice, to question patients about the use of medicinal plants and herbal medicaments is crucial to prevent plant-medicine interactions.

Keywords : Agrimonia eupatoria; pharmacological activity; interactions; medicinal plant.

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